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Fast Facts

A brief refresher with useful tables, figures, and research summaries

Common Procedures

The emergency department (ED) provides many opportunities to learn about and participate in performing bedside procedures. Some of the procedures most commonly encountered in the pediatric ED are discussed in this section.

Preparation for procedures: It is important to prepare both the child and the parents for procedures in the ED. This includes explaining the procedure and its risks to both parent and child, obtaining parental consent for all legal minors, and obtaining assent in older children and adolescents. Child life specialists (or other team members) can help explain the process to children in a developmentally appropriate way, provide calming and distraction techniques throughout the procedure (reducing the need for procedural sedation), and assess the need for medical anxiolysis. (See NEJM Videos in Clinical Medicine on Managing Procedural Anxiety in Children.)

Laceration Repair

Lacerations account for 30% to 40% of injury presentations to the pediatric ED. The most common mechanisms of laceration among children include blunt trauma, contact with a sharp object, and bites (both animal and human). Because lacerations are so common among injured children, EM providers must be comfortable with optimal methods for laceration repair — focusing on achieving hemostasis, preventing infection, and optimizing cosmesis. Often, these goals may prove difficult to accomplish on an active, mobile, or crying pediatric patient. (See NEJM Videos in Clinical Medicine on Basic Laceration Repair and the CHOP Emergency Department Clinical Pathway for Evaluation/Treatment of Children with a Laceration .)

Lumbar Puncture

During lumbar puncture (LP), cerebrospinal fluid (CSF) is extracted from a patient’s spinal canal through a hollow-bore needle. The procedure can be both diagnostic (e.g., for meningitis), and therapeutic (e.g., for idiopathic intracranial hypertension). In the ED, lumbar punctures can help with diagnosis and dictate patient disposition. (See NEJM Videos in Clinical Medicine on Lumbar Puncture.)

LP Preprocedure Checklist

LP is performed under sterile conditions. In addition to sterile gown, gloves, drapes, and dressings, the procedure requires the following:

  • chlorhexidine or povidone-iodine antiseptic solution with applicator swabs

  • topical 4% lidocaine cream

  • 1% lidocaine without epinephrine with needle and 3-mL syringe

  • four plastic test tubes

  • three-way stopcock

  • CSF manometer

  • 22-gauge spinal needle

    • age <1 year: use 1.5-inch needle

    • age >1 year through school age: use 2.5-inch needle

    • adolescent or larger habitus: use 3.5-inch needle

LP Procedure Instructions

  • Apply 4% lidocaine cream to the intended LP site 45-60 minutes prior to the procedure.

  • Position the patient in the left lateral decubitus or upright position and maximally flex the spine.

  • Locate the intervertebral spaces between either L3 and L4 or between L4 and L5 using the iliac crest as a guide. Data have demonstrated the utility of ultrasound guidance in locating intervertebral spaces.

  • Don a sterile gown and gloves and clean a large area around the targeted vertebral space three times with antiseptic solution.

  • Anesthetize the area with 1% injectable lidocaine and allow time for it to take effect (1-2 minutes).

  • Insert the spinal needle into the skin with the bevel facing toward the ceiling.

  • Advance the needle slowly, angled slightly toward the umbilicus, until a decrease in resistance is felt; this “pop” is rarely felt in neonates and young infants.

  • Remove the stylet from the spinal needle, and if CSF flows out, attach the manometer to the end of the spinal needle using the three-way stopcock and record the opening pressure. If CSF does not flow, reinsert the stylet and advance or reposition the needle carefully until it is obtained.

  • Collect approximately 1 mL in each of the four tubes.

  • Reinsert the stylet prior to removing the needle from the patient.

  • Place a bandage over the puncture site and clean the surrounding area.

LP Complications

Common complications from LP include headache and localized back pain. Less common complications include infection, hematoma, and epidural CSF leak. In neonates, positioning can cause hypoventilation and occasionally apnea. LP should be performed with caution in infants with preexisting respiratory compromise.

Procedural Sedation

Some procedures in the pediatric ED require the child to remain motionless (e.g., laceration repair across the vermilion border), while other procedures are particularly painful (e.g., closed-fracture reduction). Procedural sedation is a common method for alleviating the pain and stress associated with these procedures for both children and caregivers. Therefore, learning to provide safe and effective procedural sedation is an integral part of pediatric emergency training.

The American College of Emergency Physicians (ACEP) defines procedural sedation as “a technique of administering sedatives or dissociative agents with or without analgesia to induce a state that allows the patient to tolerate unpleasant procedures while maintaining cardiorespiratory function.” (See NEJM Videos in Clinical Medicine on Procedural Sedation and Analgesia in Children and the CHOP Emergency Department Clinical Pathway for Procedural Sedation.)

Four Depths of Procedural Sedation
Level Purposeful Response Maintains Airway Maintains Cardiovascular Function
Minimal Verbal commands Yes Yes
Moderate Verbal commands +/- light tactile stimulation Yes Yes
Deep Painful stimulation Potentially no Yes
Anesthesia None No Potentially no

Common Indications for Procedural Sedation

Common indications of procedural sedation include fracture reductions, incision and drainage of abscesses in sensitive areas, wound care, prolonged diagnostic imaging (e.g., MRI), lumbar punctures, any procedure requiring complete stillness from a patient who is not developmentally able to remain motionless on command.

Procedural Sedation Preprocedure Checklist

  • Obtain history and perform physical assessment, looking for any contraindications (habitus, sleep apnea, chronic respiratory illness, airway anomalies, allergies).

  • Determine fasting time.

    • clear liquid: 2 hours

    • breastmilk: 4 hours

    • infant formula:6 hours

    • solids: 6-8 hours

  • Choose route of administration.

    • commonly delivered intravenously (IV)

    • can be delivered intranasally (IN), intramuscularly (IM), or subcutaneously (SQ)

  • Explain the procedure to the caregiver and child and obtain consent and assent when appropriate.

  • Gather equipment needed for monitoring:

    • vital signs: cardiorespiratory monitor, blood-pressure cuff, pulse oximetry, end-tidal carbon dioxide (CO2) monitor

    • airway: flow-inflating bag and mask, artificial-airway supplies ready

    • medications: reversal drugs, rapid-sequence intubation medications, in case an advanced airway becomes necessary

Commonly Used Drugs for Procedural Sedation in Children
Medication Onset Duration Onset
Ketamine 30 seconds 5-10 minutes Sedative and analgesic
Vital signs changes: hypertension and bradycardia
Adverse effects: agitation, emesis, hypersalivation
Other: preserves airway reflexes, long recovery time
Propofol 30 seconds 3-10 minutes Sedative and amnestic
Vital signs changes: hypotension and bradycardia
Adverse effects: respiration depression
Other: narrow therapeutic range
Midazolam 1-5 minutes 20-30 minutes Anxiolytic and amnestic
Adverse effects: respiratory depression
Other: short-acting

Procedural Sedation Postprocedure Checklist

  • monitor until patient returns to age-appropriate baseline mental status

    • patient has stable vital signs

    • consider ability to tolerate fluids prior to discharge home

Rapid-Sequence Induction for Intubation

Endotracheal intubation is indicated in any clinical scenario wherein a child is at risk of impending respiratory failure or is otherwise unable to maintain their own natural airway. In the pediatric population, this scenario is often the result of neurological failure (e.g., status epilepticus or intracranial injury). The primary goal of intubation is the prompt and accurate placement of an artificial airway while maintaining hemodynamic stability. In the ED, this is usually accomplished using rapid-sequence induction.

Intubation Preprocedure Checklist

  • cardiorespiratory monitor with capnography capability

  • bag-valve mask and oxygen source

  • suction system

  • IV access

  • endotracheal tube (ETT) and stylet

    • age-based formula for choosing ETT size: 4+ (age in years/4)

    • have available tubes a half size smaller (in case of difficulty passing ETT) and larger (in case of large air leak)

  • laryngoscope with appropriately sized blade

    • direct visualization

    • indirect visualization (e.g., fiber-optic laryngoscopy)

    • blade sizing:

      • newborn to young infant: sizes 0-1, straight blade

      • infant to toddler: size 1, straight blade

      • small to school-aged child: size 2, straight or curved blade

      • large child or teen: sizes 2-3, straight or curved blade

  • consent from caregiver (not required if emergent and no caregiver present)

  • emergency plan and materials in case of difficulty passing ETT:

    • oral and nasal airways available

    • laryngeal mask airway available

    • back-up provider experienced with intubation (i.e., anesthesiologist, critical care physician, neonatologist) available

Sedatives: Sedatives are used to induce unconsciousness prior to intubation. Ideally, they are rapid in onset and have little effect on hemodynamics.

Sedative Medications for Intubation in Children
Agent Effects Clinical Comments
Ketamine Analgesic and dissociative properties
Increases HR and BP
Bronchodilator effects
Good for hypotension/shock and
asthmatics
Avoid if concerned for increased
intracranial pressure (a theoretical risk)
Etomidate Rapid onset and short duration
Minimal hemodynamic effects
Good for head trauma
Avoid if concerned for septic shock (may
cause adrenal suppression)
Midazolam Anticonvulsive and amnesic properties
Variable dosing needed for induction
Good for status epilepticus and
hypertensive patients

Neuromuscular Blockade: Neuromuscular blocking agents are used to induce paralysis in order to optimize passage of the endotracheal tube. Paralytic agents should only be administered after a sedative agent has already been given.

  • Depolarizing agents cause muscle fasciculations prior to paralysis, which can lead to muscle pain, hyperkalemia, and a higher risk of malignant hypertension.

  • Nondepolarizing agents do not cause fasciculations prior to paralysis and thus cause none of the side effects mentioned above.

Drugs for Neuromuscular Blockade
Depolarizing Agent Effects Clinical Considerations
Succinylcholine Rapid onset
(30 to 60 seconds)
Short duration
(3 to 8 minutes)
Transient bradycardia
Avoid in patients with
hyperkalemia or
risk of neuromuscular
disease
Nondepolarizing Agent Effects Clinical Considerations
Rocuronium Onset: 1 to 3 minutes
Duration: 30 to 45 minutes
Larger doses: quicker onset
but longer duration
No contraindications
Vecuronium Longer onset than
rocuronium
Larger doses: quicker onset
but longer duration
No contraindications

Other Medications: Although data are limited on the benefit of administering the following adjunct medications during endotracheal intubation, they are still used in select clinical scenarios. Both are used for premedication prior to intubation.

Adjunct Medications for Endotracheal Intubation
Agent Effects Clinical Indication
Atropine Vagolytic; may reduce reflex
bradycardia during laryngoscopy;
reduces oral secretions
Age <1 year
Age <5 years receiving succinylcholine
Can be used in conjunction with ketamine to reduce secretions
Lidocaine May attenuate increase in
intracranial pressure during
laryngoscopy
Traumatic brain injury and concern for
existing elevated intracranial pressure

Postprocedure Checklist

  • Auscultate for bilateral and equal breath sounds.

  • Attach ETT to end-tidal carbon dioxide monitoring.

  • Confirm optimal placement with chest radiograph.

  • Secure tube once desired position in the trachea is confirmed.

    • Rule of thumb for securing ETT: 3 x the internal diameter of the ETT (e.g., 12 cm for a 4.0 ETT)

Research

Landmark clinical trials and other important studies

Research

The Effect of Bedside Ultrasonographic Skin Marking on Infant Lumbar Puncture Success: A Randomized Controlled Trial

Neal JT et al. Ann Emerg Med 2017.

This prospective, randomized-controlled trial suggests that ultrasonography-assisted site marking improves infant lumbar-puncture success rates.

Read the NEJM Journal Watch Summary

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Risk Factors for Adverse Events in Emergency Department Procedural Sedation for Children

Bhatt M et al. JAMA Pediatr 2017.

This prospective, multicenter, observational cohort study demonstrates that ketamine has the fewest serious adverse events when used alone for procedural sedation.

Read the NEJM Journal Watch Summary

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A Comparison of Cosmetic Outcomes of Lacerations on the Extremities and Trunk Using Absorbable Versus Nonabsorbable Sutures

Tejani C et al. Acad Emerg Med 2014.

This randomized, controlled trial shows the cosmetic noninferiority of absorbable sutures over nonabsorbable sutures on the limbs and trunk.

Read the NEJM Journal Watch Summary

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Pediatric Lumbar Puncture and Cerebrospinal Fluid Analysis

Bonadio W. J Emerg Med 2014.

A review of the anatomic, physiologic, and pathologic aspects of performing pediatric lumbar punctures

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Reviews

The best overviews of the literature on this topic

Reviews

Procedural Sedation and Analgesia in Children

Krauss B and Green SM. Lancet 2007.

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Guidelines

The current guidelines from the major specialty associations in the field

Guidelines

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Red Book: 2018 Report of the Committee on Infectious Diseases

Kimberlin DW et al. American Academy of Pediatrics 2018.

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Additional Resources

Videos, cases, and other links for more interactive learning

Additional Resources

Procedural Sedation and Analgesia in Children

Krauss BS, Krauss BA, and Green SM. N Engl J Med 2014.

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Basic Laceration Repair

Thomsen TW et al. N Engl J Med 2006.

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Lumbar Puncture

Ellenby MS et al. N Engl J Med 2006.

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